PIRFENIDONE INHIBITS HYPOXIC PULMONARY HYPERTENSION THROUGH THE NADPH/ROS/P38 PATHWAY IN ADVENTITIAL FIBROBLASTS IN THE PULMONARY ARTERY

Pirfenidone Inhibits Hypoxic Pulmonary Hypertension through the NADPH/ROS/p38 Pathway in Adventitial Fibroblasts in the Pulmonary Artery

Hypoxic pulmonary hypertension (HPH) is a devastating disease characterized by progressive vasoconstriction and vascular remodeling.Pirfenidone (PFD) inhibits the progression of HPH, though the molecular mechanisms remain 154 unknown.This study is aimed at determining the role and mechanism of PFD in HPH in human pulmonary artery adventitial fibrob

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Acute Portomesenteric Venous Thrombosis following Laparoscopic Small Bowel Resection and Ventral Hernia Repair

Acute portomesenteric venous thrombosis is a rare but life-threatening complication of laparoscopic surgery that has been described in literature.Prompt diagnosis MONTPELLIER RMC61DFC 60cm Dual Fuel Cooker Cream Black and early initiation of treatment are vital to prevent life-threatening complications such as mesenteric ischemia and infarction.A 5

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Employing Molecular Conformations for Ligand-Based Virtual Screening with Equivariant Graph Neural Network and Deep Multiple Instance Learning

Ligand-based virtual screening (LBVS) is a promising approach for rapid and low-cost screening of potentially bioactive molecules in the early stage of drug discovery.Compared with traditional similarity-based machine learning methods, deep learning frameworks for DVD Recorders LBVS can more effectively extract high-order molecule structure represe

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The Institutional Design of Modern Social Movements

Modern scientists, determining the features of social movements, investigate MONTPELLIER RMC61DFC 60cm Dual Fuel Cooker Cream Black the institutional environment, cultural and material flows, communicative practices, and conditions affecting the activities of the participants.In the course of multidirectional activity, movements create new "communi

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